Flores Synthesis of [26-13C]-Lanosteral from Lanosterol with Schema for Vitamin D Agonist as Drug Candidate for Chronic Inflammation-type Disease Aetiology.
This Undergraduate thesis dates from research in 1980 at Kalamazoo College USA on steroidal chemistry beginning the journey with elaborating the side-chain of Lanosterol (animal, fungi). As a precursor to experiments described for VitD analogues or agonistes (we call here VitD-As) for potential anti-chronic inflammatory drugs we hope will have eventual use as a preventative health nutritional (PHN) with heart-health drug applications. Potential use of semi-labour, plant-based aquaponics marine grass land-based cropping using our chemically- synthesized Lanosterol (animal, fungi) derivative introduced by reusable intra-tissue plant implant above the root / stem junction (uptake by s. osmotic pressure), to a timed delivery dosage to fully harvest of leafy parts, with downstream processing to extract bioactive forms of UV-protected VitD-As using rec-chloroplastid expressed genes in leaves, is referred to. For more reading: Go to:http://dannflores9. wordpress.com.